The authors discuss the advantages of microreactors and flow chemistry for various reaction types in achieving improved process economics and reaction efficiency. This article is part of PharmTech's ...

Crystallization often sits at the heart of product quality, yield, and downstream efficiency. For many plants, the choice ...

Fueled by a need to reduce costs and improve efficiencies, continuous processing may be the next paradigm shift in pharmaceutical manufacturing. Although common in other process manufacturing ...

The antibiotic cefazolin is an essential drug according to the World Health Organization (WHO). It is usually produced via batch manufacturing, but this multistep process is time-consuming, wasteful ...

Indian pharma could consider continuous flow processing technology which is a cost-effective alternative to batch processing. This is because consistency in manufacture is an ongoing challenge. Flow ...

Transpeptidation catalyzed by sortase A allows the preparation of proteins that are site-specifically and homogeneously modified with a wide variety of functional groups, such as fluorophores, PEG ...

Pharmaceutical manufacturing has traditionally been performed using batch process techniques. Batch processes have been proven over many decades of use, but can have shortcomings when it comes to ...

Historically, pharmaceutical products have been produced in a traditional ‘batch’ system, in which every operation is executed separately using a defined quantity of materials. In batch manufacturing ...