This article introduces the field of bioinformatics and its importance as a cornerstone of biological research, as well as its history from the comparative analysis of the first amino acid sequences ...
As the rate of sequencing increases, greater throughput is demanded from read aligners. The full-text minute index is often used to make alignment very fast and memory-efficient, but the approach is ...
In bioinformatics, multiple sequence alignment (MSA) is an NP-hard problem. Nature-inspired approaches can provide an approximate solution compared to conventional approaches. In this article, the MSA ...
Many cellular processes, including transcription and DNA replication, critically depend on chromatin structure, the three-dimensional organization of DNA that includes nucleosome positioning and ...
The Genome Multitool (GEM) mapper rapidly and accurately provides all alignments of a read within a user-defined number of mismatches. Over the past several years, the flood of data produced by second ...
In a new article, researchers explain their work on computer-assisted approaches towards surveillance and consequent design of drugs and vaccines to combat the growth and spread of the Zika virus. The ...
The declining cost and increasing accessibility of next-generation sequencing (NGS) have led to the permeation of these techniques throughout the life sciences. The sequencing data generated from many ...
Parabon® NanoLabs' Dr. Ellen Greytak will be a featured speaker in the Sexual Assault Kit Initiative (SAKI)'s Webinar "Emerging DNA Techniques." Reston, Va. (March 2018) - Parabon® NanoLabs, a ...
Researchers at DESY’s Center for Free-Electron Laser Science, along with colleagues from around the world, recently showed that laser-induced alignment can be accomplished to significantly improve ...
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