The American Journal of Managed Care

CD4/CD8 Ratio a Useful Predictor of Mortality in Patients Living With HIV

A review found that CD4/CD8 ratio could be used as a prognostic marker for mortality in patients with HIV, though future studies need to be done to confirm these findings. Clinical practices can ...
MedPage Today on MSN

CAR-T Immune Toxicity Linked to Non-Relapse Mortality Risk in Myeloma

Study suggests CD4+ T cells mediate these immune-related toxicities ...
eLife

HIV-specific CD8+ T-cell proliferative response 24 weeks after early antiretroviral therapy initiation is associated with the subsequent reduction in the viral reservoir

In individuals who started antiretroviral therapy during acute HIV infection, the proliferative capacity of HIV-specific CD8+ ...
Hosted on MSN

Understanding Absolute CD4 Count and CD4 Percentage

Measuring CD4 T-cells is important in helping healthcare providers determine the stage and possible complications of HIV infection. While they are no longer used to determine when HIV therapy should ...
EurekAlert!

Evolutionary conservation of CD4 and LAG-3 and their cytoplasmic tail motifs with opposing immune functions: do we finally understand LAG-3?

Conservation of their respective cytoplasmic tail motifs, CxC/H in the case of CD4 and an ITIM-like motif in the case of LAG-3, supports that competition between CD4 and LAG-3 for binding of kinase ...