Scientists have discovered a new CRISPR mechanism with precise activity, expanding the potential applications of the existing CRISPR toolbox.

The CRISPR “gene scissors” have become an important basis for genome-editing technologies in many fields, ranging from biology and medicine to agriculture and industry. A team from the Helmholtz ...

A bacterial defense system called SPARDA employs kamikaze-like tactics to protect cells and could be useful in future ...

CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations ...

Genetic disorders occur due to alterations in the primary genetic material—deoxyribonucleic acid (DNA)—of an organism.

Researchers uncovered a previously unknown CRISPR immune response in bacteria that targets transfer RNAs. The newly ...

(Nanowerk News) The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to antiviral therapies and diagnostics. However, to safely harness ...

CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based gene therapy. However, until now, the precise mechanism of exactly how ...

Co-founded by Jennifer Doudna and Fyodor Urnov, the company intends to simultaneously develop many gene editing treatments for rare conditions by using the agency’s “plausible mechanism” pathway.

Infection with the pathogenic yeast fungus Candida auris (C. auris) can wreak havoc on the health of hospital patients and ...

CRISPR-Cas is an adaptive immune system of prokaryotes (bacteria and archaea). Apart from protecting its host against invading viruses, alternative biological functions of CRISPR-Cas have also been ...

A novel CRISPR defense mechanism, unlike known nucleases, specifically destroys transfer ribonucleic acids (tRNA) that are vital for protein production to shut down infected cells. (Nanowerk News) ...