Explore scalable strategies for iPSC-derived islet differentiation using GMP-grade activin A and KGF to advance diabetes ...

A team at Johns Hopkins Medicine has focused their work on myelin development using oligodendrocytes to help study conditions like MS.

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

Cilia are evolutionarily conserved, microtubule-based organelles that project from the surface of most eukaryotic cells and play a central role in sensing ...

Understanding how cells transform into specialized types during human development is a central challenge in biology. This complex process, known as cell differentiation, holds the key to understanding ...

A large genetic screen has revealed how stem cells transform into brain cells, exposing hundreds of genes that make this process possible. Among the discoveries is PEDS1, a gene now linked to a ...

In experiments with mice, Johns Hopkins Medicine scientists report new evidence that precursors of myelin-producing cells—one ...

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer ...

Discover the challenges of acute myeloid leukaemia linked to inflammatory cell death and the quest for effective therapies.

New evidence shows that precursors of myelin-producing cells — one of the few #brain cell types that continue to be produced ...