A small number of cancer cells with the ability to change their identities and behaviors appear to be a key driver of cancer ...

A small subpopulation of highly plastic cancer cells has been found to be for cancer progression and treatment resistance.

Cancer cells expand through mutations – but not just through mutations. They also change their behavior in the absence of underlying genetic alterations. Such plasticity helps the cells both adapt to ...

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more ...

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more ...

Plasticity in cancer cells describes their inherent ability to undergo alterations and turn certain features on and off at different times. This flexibility sometimes occurs as a result of epigenetic ...

“There has never really been an integrated explanation as to why cancer cells develop plasticity,” said Antonio Iavarone, M.D. “That’s what our study does. We’ve now revealed how the plasticity of ...

The study, published in British scientific journal Nature, suggests that the disease may begin in basal stem cells — long-lived cells that help repair and replace damaged tissue in the lungs — ...