Cilk1 deficiency disrupts normal tooth development by altering primary cilia function and weakening Hedgehog signaling. This ...

In many cells of the human body, hair-like protrusions known as cilia act as antennae, allowing cells to receive signals from their environment and other cells. As cells grow and divide, each cilium ...

Primary cilia are sensory organelles present on the cell surface; however, their physical structure has not been defined due to technical reasons. A new PNAS study examined primary cilia in human ...

Many cells in our body have a single primary cilium, a micrometer-long, hair-like organelle protruding from the cell surface that transmits cellular signals. Cilia are important for regulating ...

A historically overlooked rod-like projection present on nearly every cell type in the human body may finally be getting its scientific due: A new study has found that these appendages, called cilia, ...

Researchers have uncovered a synapse on neurons’ tiny hair-like structures, which may facilitate long-term changes to genomic information in the nucleus. A new study from the Howard Hughes Medical ...

Left-right asymmetry is known to be established during early embryogenesis by a small cluster of cells termed the left-right organizer. Within this organizer, motile cilia beat rapidly to create a ...

Although the human body is externally symmetric across the left-right axis, there are remarkable left-right asymmetries in the shape and positioning of most internal organs including the heart, lungs, ...

Sanja Sviben and Alexander Polino, Washington University in St. Louis. In her lab at Washington University in St. Louis, endocrinologist Jing Hughes studies a peculiar structure that sticks out of the ...