University of Alabama at Birmingham researchers, for the first time ever, have achieved patch-clamp studies of an elusive part of mammalian myelinated nerves called the Nodes of Ranvier. At the nodes, ...

The core mechanism of intracellular vesicle fusion consists of SNAREpin zippering between vesicular and target membranes. Recent studies indicate that the same SNARE-binding protein, complexin (CPX), ...

Researchers have discovered a molecular 'clamping' mechanism within a male-specific protein-DNA complex whose mutation causes sex reversal: children with XY chromosomes but female bodies, a condition ...