The long journey from cell culture to a purified monoclonal antibody (mAb) involves many sample processing steps, with clarification and filtration playing significant roles. However, clogs, complex ...

There can be a reluctance to clarify (appeal) the findings of a Joint Commission final accreditation report, especially as there’s not a lot of information available regarding the process to follow.

Optimizing the clarification of cell culture or fermentation broth is generally seen as a limited contributor to critical quality attributes (CQA). Researchers at Merck, however, say it’s time to ...