The long journey from cell culture to a purified monoclonal antibody (mAb) involves many sample processing steps, with clarification and filtration playing significant roles. However, clogs, complex ...
Optimizing the clarification of cell culture or fermentation broth is generally seen as a limited contributor to critical quality attributes (CQA). Researchers at Merck, however, say it’s time to ...
A conventional production fed-batch process involves a multi-stage seed expansion and elaborate clarification steps to isolate the protein of interest from other process impurities. The current ...
WESTBOROUGH, MASSACHUSETTS, June 24, 2020 — Pall Laboratory, a global leader in proven filtration, separation and sample preparation solutions, has introduced two AcroPrep™ 24-well filter plates. The ...
Recombinant proteins can be produced using many types of cells including, yeast, bacteria, insect and mammalian cells. What advantages are there to producing recombinant proteins using mammalian cells ...