Figure 1: Three distribution patterns of histone acetylations. Figure 2: Patterns of histone modifications associated with promoters. To correlate each modification with gene expression, we compared ...

About 20 years ago, the industry-wide cost of a new drug was around $100 million (USD). Toward the end of the 1980s, that cost had risen to $250 million. Biological testing had entered the ...

Not so long ago, received wisdom in the psychology of trading and investing in financial markets said that the key to success was consistency. Once you found your probabilistic “edge” in markets, you ...

Genome-scale CRISPR screens in cancer cell lines have enabled the unprecedented identification of genome-scale vulnerabilities and co-dependencies. However, a significant obstacle in identifying ...

A framework based on advanced AI techniques can solve complex, computationally intensive problems faster and in a more more scalable way than state-of-the-art methods, according to a new study. A ...

Using combinatorial chemistry, researchers have designed a new class of metallic glasses that works well at high temperatures and should be easy to form into useful components (Nature 2019, DOI: ...

Recent technological advances have set the stage for a renewed focus on human-based solutions called new approach ...

Conventional quantum algorithms are not feasible for solving combinatorial optimization problems (COPs) with constraints in the operation time of quantum computers. To address this issue, researchers ...