Plowing through Transcriptional Variations by Harnessing the Powerful Next-Gen Technique Advances in genomics over the past several years have had a profound impact on our grasp of molecular biology ...

In 2005, two landmark papers describing novel cycle-array sequencing methods ushered in a new era in genetics. Known at the time as next-generation sequencing (NGS), these methods are now more ...

This study generated two million short DNA sequences, known as signature sequences or sequence tags, to identify and quantify both known and novel small RNA molecules. with the Breaking Science News ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

Hospital for Sick Children in Toronto researchers are reporting that targeted RNA sequencing can detect clinically actionable alterations in 87% of tumors and provide decisive findings where DNA-seq ...

A thorough evaluation of the transcriptome is provided by high-resolution RNA analysis using next-generation sequencing (RNA-seq), enabling the measurement of global gene expression. The use of ...

An international research team has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time ...