The triplication of a region of chromosome 21 around D21S55 in 21q22.2–22.3 has been involved in the main features of Down syndrome including mental retardation (Down syndrome chromosome region: DCR).

Restriction site maps of chloroplast DNA (cpDNA), maternally inherited in Clarkia, were obtained in representative species of all seven diploid sections, the allotetraploid sect. Clarkia, and the ...

Optical mapping is a powerful genetic identification tool that so far has been limited to lower organisms. Now a USC-led team of computational biologists has made the method practical for human ...

A long-range optical DNA mapping technique has proved its worth in a clinical setting, successfully identifying large structural variants in DMD, the gene responsible for Duchenne muscular dystrophy.

DNA from a variety of uninfected chicken cell types has been analyzed by using restriction endonuclease digestion and RPC-5 ion-exchange chromatography followed by agarose gel electrophoresis.