Researchers have made discoveries regarding the effect of the dipeptide Leucine-Histidine (LH) in suppressing microglial activation and depression-associated emotional disturbances. LH dipeptide is ...
A research group led by Professor Tomoyuki Furuyashiki and Associate Professor Shiho Kitaoka (Graduate School of Medicine) in collaboration with researcher Yasuhisa Ano of Kirin Holdings have made ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, No. 28 (July 13, 2010), pp. 12652-12657 (6 pages) The dipeptide N-acetylglutaminylglutamine amide (NAGGN) was ...
This new article publication from Acta Pharmaceutica Sinica B, discusses how ALS-linked C9orf72 dipeptide repeats inhibit starvation-induced autophagy through modulating BCL2–BECN1 interaction.
Heme, a major iron source, is transported through the outer membrane of Gram-negative bacteria by specific heme/hemoprotein receptors and through the inner membrane by heme-specific, periplasmic, ...
Figure 1: Ribbon diagram of the eNOS heme domain, the active site and the dipeptide inhibitors used in this study. To uncover the structural basis for why inhibitors I, II and III (Fig. 1a) exhibit ...
New research published in EPJ D combines mass spectroscopy with a range of other simulation and analytical techniques, allowing researchers to distinguish between two chiral forms of a dipeptide ...
How do expanded hexanucleotide repeats in the C9ORF72 gene cause amyotrophic lateral sclerosis and frontotemporal dementia? They give rise to aberrant dipeptide repeat proteins, but even though these ...
Run-on repeats of a hexanucleotide sequence in the C9ORF72 gene are the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). According to a March 29 ...
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