As thoroughly covered in your recent article (C&EN, Oct. 28, 2024, page 26), the issue of replacing the traditional natural product test for endotoxin, limulus amoebocyte lysate (LAL), with a ...

Endotoxin testing is critical in industries such as biopharmaceuticals and medical devices to ensure product safety and reliability. Endotoxins, which are lipopolysaccharides (LPS) found in ...

Endotoxin refers to a component of the outer cell membrane of Gram-negative bacteria called lipopolysaccharide (LPS). LPS is the biologically active portion of naturally occurring endotoxin complexes.

New standards may help push more drugmakers to use a synthetic product for critical drug safety testing, instead of one made from horseshoe crab blood that has long drawn criticism. The U.S.

In this episode of C&EN Uncovered, host Craig Bettenhausen speaks with C&EN assistant editor Laurel Oldach about the use of horseshoe crab blood in pharmaceutical endotoxin testing, the challenges of ...

Next generation robotic endotoxin testing system boosts manufacturing productivity in the lab Automation through robotics represents an evolution of bacterial endotoxin testing and streamlines quality ...

In this webinar, attendees will be provided an overview of the technologies that currently exist for bacterial endotoxins testing (BET), and the drawbacks associated with each. Microfluidic technology ...

The presence of harmful bacteria in parenteral drugs or implantable devices can cause inflammatory responses such as fever and, in some cases, may even be fatal. As a result, robust bacterial ...

With the introduction of pioneering technology for bacterial endotoxins testing (BET), it is critical to demonstrate equivalency across platforms. The Sievers Eclipse Ratio Verification Test was ...

Endosafe ® Trillium™ recombinant cascade reagent (rCR) cartridges from Charles River Laboratories were designed to provide an alternative option to bolster commitments to sustainability and animal ...