Brazilian researchers have found that stellate pancreatic cells produce periostin, which reshapes surrounding tissue and allows tumors to spread more easily, helping explain why the disease is so ...

Researchers at Children's Hospital Los Angeles have discovered a key difference between the two main types of rhabdomyosarcoma—paving the way for more targeted treatments. The study, led by JinSeok ...

“This review explores our current understanding of how ECM geometry influences the behaviors of both immune cells and tumor cells, which in turn impacts treatment efficacy and cancer evolutionary ...

In a study published in the Journal of Extracellular Vesicles, scientists from the UF Health Cancer Institute have found a way to make treatment for a notoriously aggressive breast cancer more ...

A new Brazilian study has revealed the key role of the protein periostin and stellate pancreatic cells in allowing pancreatic ...

CAFs Impact ECM and tumor growth: CAFs secrete MMPs to degrade ECM, releasing growth factors for cancer cells. ECM changes counteract CAFs and tumor cells: (a) Hard ECM triggers Twist release from ...

These fiber-producing cells, or fibroblasts, make collagen and the extracellular matrix that gives shape and structure to our tissues. Fibroblasts can be found in many solid tumors, but they are ...

A new international study led by Prof. Carmit Levy of the Department of Human Genetics and Biochemistry at the Gray Faculty ...

All cells, from bacteria to mammalian cells, produce extracellular vesicles—tiny membrane-enclosed packages of bioactive cargo. 1 Until relatively recently, scientists believed these organic ...