(A) Immunofluorescence staining of HCV-core protein in HCV replicating Huh7 cells. (B) FACS analysis of EpCAM and CD44 expression in HCV replicating Huh7 cells. (C) RTD-PCR analysis of HCV-RNAin ...

Small Molecule Combination Therapies Are Being Investigated to Increase Response Rates Researchers agree that now is a crucial time to be involved in hepatitis C virus (HCV) research. “Current ...

Model showing how fatty acid metabolism triggers lipid peroxidation and regulates hepatitis C virus replication. Production of polyunsaturated fatty acids (PUFAs) is regulated predominantly by FADS2.

Occult HCV and HBV infections are recently identified entities whose existence became evident when nucleic acid amplification assays of enhanced sensitivity were employed for the detection of viral ...

Figure 1. The direct-acting antiviral targets in the hepatitis C virus replication cycle. NS3/4A protease inhibitors target the NS3/4A protease enzyme which is needed for the virus to develop the ...

Present interferon-based therapy for chronic hepatitis C is limited by both efficacy and tolerability. Telaprevir and boceprevir are the first two direct-acting antiviral drugs (DAAs) that inhibit ...

Not Just an Epidemic of Painkillers: An Epidemic of Pain Chronic hepatitis C virus (HCV) infection increases the risk for several types of cancer, including hepatocellular carcinoma (HCC) and B-cell ...