Genetic linkage analysis can be used as a tool for estimating the genetic distance between two loci. In family data, a small recombination fraction between a hypothesized disease locus and a genetic ...
In a paper published on March 28 in Sciencexpress, Rachel Brem and colleagues describe how linkage analysis and gene expression profiling can be combined to dissect transcriptional regulatory networks ...
Background: The International Type 2 Diabetes Linkage Analysis Consortium was formed to localize type 2 diabetes predisposing variants based on 23 autosomal linkage scans. Methods: We carried out meta ...