In a novel study, researchers introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain- and loss-of-function variants across the genome. Unlike current methods that ...

In a novel study, researchers from the Icahn School of Medicine at Mount Sinai introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain- and loss-of-function variants across ...

Outcomes in patients with pancreatic and ampullary cancer whose tumors harbor pathogenic APC mutations. Utility of circulating tumor DNA (ctDNA) for the detection of minimal residual disease (MRD) ...

The system of long noncoding RNA (lncRNA)–mediated transcriptional interference that represses fission yeast phosphate homoeostasis gene pho1 provides a sensitive readout of genetic influences on ...

Activists want it banned. The US government may soon further restrict it. And politicians won’t stop talking about it. So-called “gain-of-function” pathogen research has faced growing scrutiny ever ...