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Study shows DHPS enzyme controls macrophage maturation across multiple organs

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer ...
Kaleido Scope

In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal function

Macrophages are the specialized phagocytic cells that respond to toxic particle depositions to exert inflammatory and clearance responses. These long-lived immune cells engulf foreign substances like ...
New Atlas

A single inflammatory switch may help repair the liver

Chronic liver disease gets worse when the liver's immune system stays overactive, resulting in ongoing inflammation and ...
EurekAlert!

In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal function

The understanding of how macrophages regulate their response to toxic particles via two independent pathways could uncover therapeutic opportunities to quell inflammation BIRMINGHAM, Ala. – Human ...