Mitochondrial dysfunction is associated with various chronic diseases and cancers, including neurodegenerative diseases and ...

Cirrhotic cardiomyopathy (CCM) is a significant complication of cirrhosis, but its progression and underlying mechanisms ...

Pretzel Therapeutics is advancing its mitochondrial disease therapies, pushing lead candidate PX578 through Phase 1 trials ...

The first healthy volunteers have been dosed in an early clinical trial testing NRG5051, a disease-modifying therapy for ALS ...

New Review Integrates Human, Animal, and Cellular Evidence to Reframe AD as a Triad-Centered Disorder Alzheimer’s disease (AD ...

Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.

The Agilent Seahorse XF Mito Tox Assay kit is a powerful tool for identifying drug-induced mitochondrial toxicity by directly measuring mitochondrial oxygen consumption rates (OCR). Mitochondrial ...

Scientists have discovered that boosting the COX7RP protein enhances cellular energy efficiency and significantly extends ...

One of the most consistently reported symptoms of long COVID is the tendency for strenuous exercise to make the condition worse. Not only does long COVID reduce a person’s capacity for exercise but ...