Stanford University-led researchers report that tumor cells hijack mitochondria from immune cells, reducing anti-tumor immune ...
The tiny little powerhouses of our cells, the mitochondria, are unique among organelles because they carry their own tiny ...
Patch-clamp recordings demonstrated that LHON neurons, which typically exhibit impaired sodium and potassium currents, showed restored electrophysiological function after co-culture with MSCs.
An HIV-derived nucleoside therapy now treats rare genetic diseases by restoring mitochondrial DNA and improving muscle ...
Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ischemia/reperfusion (I/R) injury. This review sheds light on the ...
Hepatic cell carcinoma (HCC), the fifth most prevalent malignancy worldwide and the fourth leading cause of cancer-related mortality, poses significant therapeutic challenges. Despite advancements in ...
Pretzel Therapeutics is advancing its mitochondrial disease therapies, pushing lead candidate PX578 through Phase 1 trials ...
Normal metabolic activity produces reactive oxygen species (ROS) that, if not eliminated, can damage cellular components. As a result, ROS from overactive mitochondria are frequently cited as a source ...
Inside every human cell, tiny mitochondria quietly convert nutrients into usable energy, keeping organs running and immune defenses primed. Now researchers have identified a previously unknown form of ...