Chromatin-remodeling enzymes perform the formidable task of reorganizing the structure of a stable macromolecular assembly, the nucleosome. Recently published work demonstrates that the SNF2H ...

In eukaryotes, DNA is tightly wound into a complex structure called chromatin. The basic packaging unit of DNA is the nucleosome core, consisting of 147 bp of DNA tightly wrapped around a histone ...

This is a preview. Log in through your library . Abstract The effect of hyperthermia (40-48°C) on the nucleosome structure of mammalian chromatin was determined using the enzyme micrococcal nuclease.

Proceedings of the National Academy of Sciences of the United States of America, Vol. 78, No. 11, [Part 2: Biological Sciences] (Nov., 1981), pp. 6803-6807 (5 pages) Switches of the types of histones ...

Tokyo, April 14 - A research group led by Hitoshi Kurumizaka, a professor of structural biology at Waseda University, unveiled the crystal structure of an overlapping dinucleosome, a newly discovered ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

It takes a lot of packaging to squeeze DNA into the nucleus of a cell. The DNA in our chromosomes is packaged into nucleosomes, which consist of about 150 DNA base pairs wrapped around eight-protein ...