Cancer does not develop overnight. It can take decades for cancer‐promoting changes in the genome to eventually lead to the formation of a malignant tumor. Researchers at the German Cancer Research ...

How does a proto-oncogene cause cancer? In the early twentieth century, a tumor-causing virus called the Rous sarcoma virus (retrovirus) was discovered. 3 Host cell proto-oncogene (c-src) and Rous ...

Experimental drugs that directly inhibit the NSD2 enzyme have shown potential as an effective strategy against hard-to-treat cancers, such as lung and pancreatic tumors driven by KRAS mutations. The ...

Breast cancers at all stages are defined by the structure of their genomes, researchers find. Targeting these processes early is likely to offer unexpected therapeutic avenues. Breast cancers can be ...

Researchers at the University of California at San Francisco have identified an RNA-binding protein that increased the translation of Myc mRNA. The authors wrote that their work, which was published ...