For decades, the idea of resetting the biological clock sounded more like speculative fiction than clinical strategy. The discovery of Yamanaka factors by Nobel laureate Shinya Yamanaka, which can ...

As cell therapy advances toward clinical reality, iPSC-derived cellular products, in vivo reprogramming strategies, and ...

Cellular reprogramming is now hailed by its supporters as the most promising scientific approach to improving human healthspans and lifespans. Proponents claim it has the potential to reshape how — ...

Beyond headlines and promises of eternal youth, advances in transplants, epigenetic clocks, and cellular reprogramming are redefining aging to help people live longer — and, above all, healthier. Some ...

ER-300 improves key biomarkers of liver health in an animal model of MASH These data, along with additional ER-100 preclinical data from a nonhuman primate model of NAION demonstrating clear ...

A mature cell of one type can be turned into a mature cell of another type without the cell having to pass through an earlier stage of development. This is called direct reprogramming, a reliable but ...

For those hoping to cure death, and they are legion, a 2016 experiment at the Salk Institute for Biological Studies in San Diego has become liminal — the moment that changed everything. The experiment ...