This is not just another tool to image cancer. The probe is a two-for-one: detect cancer and distinguish one type from another. Together, they develop a cancer fingerprint. Determining the presence of ...

Fluorescent probes have emerged as powerful tools for the sensitive and real‐time detection of superoxide anions (O₂•⁻) in biological systems. These probes facilitate the visualisation of reactive ...

Detecting problems with lysosomes is the focus of a new set of fluorescent probes. "A lot of diseases are related to problems with lysosome functions," says a chemistry doctoral candidate involved in ...

A fluorescent probe developed by Michigan Tech chemist Haiying Liu illuminates the enzyme beta-galactosidase in a cell culture, which could help cancer surgeons. What if you could plaster cancer cells ...

Serotonin in depression is highly relevant in diagnosis, treatment, and drug development. To better study this area, a Chinese team has now developed a fluorescent probe for imaging processes that is ...

NUS chemists have developed a novel ratiometric fluorescent probe for studying cellular activity of the clinically important anticancer drug cisplatin for next generation drug development. Since its ...

Subtle cognitive decline in early Alzheimer’s disease is often indistinguishable from normal aging; as a result, the disease readily goes undiagnosed for two to three years after symptom onset. By ...

The search for answers to Alzheimer’s disease and other neurodegenerative disorders remains one of the most pressing goals in brain research. Maciej J. Stawikowski, PhD, an assistant professor of ...

Probes used in life-cell fluorescence imaging must be able to penetrate cells and bind specifically to the protein of interest. Ideally, such probes also increase their fluorescence intensity when ...

Researchers at Cornell University are working on improving the trial-and-error process that is implicated in finding effective molecules for drug delivery ...