Complex sugar-protein molecules that sense external messages to help a cell grow or respond to its environment can now be ...

Pretein design researcher Yulai Liu holds an enlarged 3D printed model from his team's efforts to design functioning calcium channels entirely from scratch. He is standing in David Baker's lab at the ...

To stay healthy, our cells rely on a self-cleaning mechanism that removes defective or unnecessary components. This process, ...

A brain protein called ANO2 has emerged as a new piece of the puzzle linking Epstein-Barr virus (EBV) infections and MS ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

Heterotrimeric G proteins, comprising Gα, Gβ and Gγ subunits, are central to the transduction of extracellular signals into precise intracellular responses in plants. These proteins not only regulate ...

Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...

A selective protein degradation system known as Golgi membrane-associated degradation (GOMED), which identifies and removes ...

This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are ...

Silent cells deep in your spinal cord may hold a surprising key to healing after devastating injuries and brain disease. A ...