New Cell-Based Assays Support Drug Discovery Across the Amylin Receptor Family STATE COLLEGE, PA, UNITED STATES, ...

The insulin receptor (IR) is a prototypical receptor tyrosine kinase that orchestrates critical cellular processes, including metabolism, cell growth and differentiation. Activation of the IR involves ...

Nerve growth factor receptor TrkA (in green) and co-receptor NRP1 (in purple) are coexpressed in the same nerve cells in mice. Researchers at the NYU Pain Research Center have found a new receptor for ...

Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a ...

Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...

A team has demonstrated new mechanisms that are involved in the development of inflammatory cardiovascular diseases. A team led by LMU researchers Christian Weber and Yvonne Döring has demonstrated ...

The histamine H3 receptor typically becomes active upon binding to one of its agonists, such as histamine itself. This, in ...

Stress, the body's natural response to different types of challenges and daily problems, is an inherently harmless state ...

Researchers have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a new study. The findings hold ...