The contractile responses of esophageal smooth muscle (SM) induced by platelet-activating factor (PAF) involve the activation of L-type voltage-dependent calcium channels (L-type VDCCs), ...
A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has ...
A new study by researchers at Yale and Johns Hopkins University has discovered how asthmatic bronchial spasms — muscle contractions in the airway that cause difficulty breathing in asthma patients— ...
image: A schematic showing how high carbon dioxide levels promote contraction of airway smooth muscle cells by increasing the cellular concentration of calcium ions (Ca2+). This material relates to a ...
A study in human and mouse heart cells identifies a faulty molecular brake in the most common form of hypertrophic cardiomyopathy, a leading cause of sudden cardiac death in young people and athletes ...